Frailty syndrome is a common geriatric syndrome characterized by a state of increased vulnerability to stressors due to age-related decline in multiple physiological systems. Individuals with frailty syndrome are at higher risk for adverse outcomes such as falls, disability, hospitalization, and mortality. Research in this area focuses on identifying risk factors, diagnostic criteria, and interventions to prevent or delay the progression of frailty in older adults. This research often involves a multidisciplinary approach, incorporating insights from geriatrics, epidemiology, and public health to better understand and address this complex and multifaceted syndrome.